Brand Names: Novalgin, Analgin, Nolotil, Dipyrone, Neo-Melubrina.

Definition: Metamizole is a powerful analgesic (pain reliever), antipyretic (fever reducer), and spasmolytic (spasm reliever) medication. It belongs to the ampyrone sulfonate family and is particularly effective for severe acute pain, such as post-operative pain, colic, or cancer pain, when other treatments are unsuitable. Although it is not classified as an NSAID, it shares some of their properties. In some countries, its use is strictly regulated or banned due to the rare but serious risk of agranulocytosis (a dangerous drop in white blood cell levels).

Brand Names: Zoloft, Lustral, Gladem, Stimuloton.

Definition: Sertraline is an antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) class. It works by increasing the levels of serotonin in the brain, a neurotransmitter that helps regulate mood, sleep, and emotions. It is widely prescribed for the treatment of major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, and post-traumatic stress disorder (PTSD).

Brand Names: Lyrica, Alzain, Axalid, Lecaent.

Definition: Pregabalin is a gabapentinoid medication used to treat chronic pain conditions and certain neurological disorders. It works by binding to specific subunits of calcium channels in the central nervous system, which helps reduce the release of neurotransmitters involved in pain signaling and seizure activity. It is primarily prescribed for neuropathic pain (such as from diabetes or shingles), fibromyalgia, generalized anxiety disorder, and as an add-on treatment for epilepsy.